Ctrl+T

Open new tab

Ctrl+W/Ctrl+F4

Close tab (or close Chrome if only one tab is open)

Ctrl+Shift+T

Reopen last tab closed. Up to 10 tabs.

Ctrl+1 through Ctrl+8

Jump to first tab, second tab, etc.

Ctrl+9

Switch to the last tab

Ctrl+Tab/Ctrl+Shift+Tab

Switch to the next / previous tab
(or use ctrl+page up/ctrl+page down)

Ctrl+N

Open new Chrome window

Ctrl+Shift+N

Open new Chrome window in incognito mode

Alt+F4

Close current window

Ctrl+left-click

Open link in a new background tab

Ctrl+Shift+left-click

Open link in a new foreground tab

Shift+left-click

Open link in a new window

Alt+left-click

Download link

Drag link to existing tab

Open link in selected tab

Drag link to tab bar

Open link in a new tab in the specified position on the tab strip.

Alt+D (or Ctrl+L)

Jump to address bar; highlights current webpage URI if available

Ctrl+E (or Ctrl+K)

Enter search query in address bar

Home/End in address bar

Jump to beginning / end of address bar

Ctrl+A in address bar

Select all text of address. Also use shift+end with cursor at beginning or shift+home with cursor at end

Type name of site and press Ctrl+Enter

Add www. to beginning and .com to end of input and opens the web address in current tab.

Type name of site and press Alt+Enter

Add www. to beginning and .com to end of input and opens the web address in new background tab.

Type search term and press Enter

Perform a search using the search engine associated with the keyword or the URI.

Type name of search engine and press Tab

Tab-to-Search feature. E.g. Typing in 'yahoo.com' plus tab opens yahoo search. Add/edit search engines via 'Under the Hood' -> Basic -> Search Engines.

F6

Alternate focus between address bar, bookmark bar and webpage

Arrow Down/Arrow Up with focus on webpage

Scroll down / scroll up

Page Down/Page Up

Scroll one page down / one page up. Also use space/shift+space

Home/End

Jump to beginning / to end of webpage

Ctrl+[+]/-

Zoom in / zoom out (or Ctrl+mousewheel)

Ctrl+0 (zero)

Return zoom to normal text size

Ctrl+U

View webpage source

F11

Turn full screen on / off

Alt+Home

Jump to homepage

Alt+Arrow Left/Arrow Right

Jump to previous webpage visited / jump to next webpage

F5/Ctrl+R

Reload current webpage

Ctrl+F5/Shift+F5

Reload current webpage with cache override

Esc

Stop webpage loading

Tab/Shift+Tab with focus on webpage

Jump to next / previous link

Enter on link

Open link in current tab

Ctrl+Enter on link

Open link in a new background tab

Shift+Ctrl+Enter on link

Open link in a new foreground tab

Shift+Enter on link

Open link in a new window

Alt+Enter on link

Download link

Shift+F10

Open context menu (simulate right mouse button)

Ctrl+A

Select all content on webpage

Ctrl+c with content selected

Copy selected content to clipboard

Ctrl+P

Print current webpage (Chrome Print Dialog)

Ctrl+Shift+P

Print current webpage (Native Windows Print Dialog)

Ctrl+O

Open file

Ctrl+S

Save current webpage

Alt+F

Open Wrench Menu (I'd call it file menu to remember the shortcut)

Ctrl+H

Open History tab

Ctrl+J

Open Downloads tab

Ctrl+F/F3

Find text on webpage. Press Enter for

Enter/Shift+Enter with text found on webpage

Find next / find previous match

Ctrl+G/Ctrl+Shift+G with text found on webpage

Find next / find previous match

Esc

With focus on Search box: Close Search box

Ctrl+Shift+B

Show or hide bookmarks bar

Ctrl+Shift+O

Open Bookmark Manager

Ctrl+D

Add bookmark for current webpage

Ctrl+Shift+D

Saves all open pages as bookmarks in a new folder

Drag URI to bookmark bar

Bookmark webpage (can be URI from address bar or link from page)

Alt+D, then F6

Jump to bookmark toolbar. Use arrow keys and enter to access bookmarks

Alt+F, then b

Open Bookmark Manager Tab

Shift+Alt+T

Set focus on the toolbar. Use arrow keys to navigate between different buttons on the toolbar.

Shift+Esc

View Google Task manager

F1

Chrome Help

Ctrl+Shift+I (or F12)

Open Developer Tools

Ctrl+Shift+J

Open Developer Tools (With Focus on Console)

Ctrl+Shift+C

Toggle Element Inspection mode

Ctrl+Shift+C (2x)

Switch Focus on Developer Tools (there is not really a shortcut for focusing on the Developer Tool, but this is a workaround. Watch the Inspector Mode Icon change color as you press for guidence. Finally, this works only if DevTools are docked; if they are not, simpy switch between windows with Alt+Tab)

?

Show General Settings Dialog (press Esc to exit)

Ctrl+[/]

Switch to next / Switch to previous panel (add Alt to the combination to reverse the direction)

Ctrl+D

Dock / Undock Developer Tool

Ctrl+Shift+M

Toggle (mobile) Device Mode

Ctrl+F

Search Text in Source

Ctrl+Shift+F

Search Text across sources

Ctrl+O

Search by Filename

Ctrl+[+]/-

Zoom in / Zoom out Developer tools

Ctrl+0 (zero)

Zoom to default

Ctrl+Arrow Up

Focus on the Elements content (this is strangely nowhere documented, but worked for me; without this one, you cannot use any of the other shortcuts below without clicking on the content first)

Arrow Up/Arrow Down

Navigate upwards/ downwards

Ctrl+Z/Ctrl+Y

Undo / Redo Change

Arrow Right/Arrow Left

Expand / Collapse

Left-click on arrow

Expand node

Ctrl+Alt+Left-click

Expand/collapse node with all children

Enter

Edit the element

H

Hide the element

F2

Toggle edit as HTML

Left-click

Edit Rule

Left-click on white space

Insert new property

Ctrl+Left-click on property

Go to line of style rule property declaration

Shift+Left-click on property

Cycle through the color definition value

Tab/Shift+Tab

Edit next / edit previous property

Arrow Up/Arrow Down

Increase / decrease value by 1

Page Up/Page Down

Increase / decrease value by 10

Shift+Page Up/Page Down

Increase / decrease value by 100

Alt+Arrow Up/Arrow Down

Increase / decrease value by 100

F8, Ctrl+\

Pause / resume script execution

F8, Ctrl+\

Pause / resume script execution

F10, Ctrl+'

Step over next function call

F11, Ctrl+;

Step into next function call

Shift+F11, Ctrl+Shift+;

Step out of current function

Ctrl+./,

Select next / select previous call frame

Left-click on line-number

Toggle breakpoint condition

Right-click on line number

Edit breakpoint condition

Alt+Delete

Delete individual words

Ctrl+/

Comment a line or selected text

Ctrl+S

Save changes to local modifications

Ctrl+Alt+S

Save all changes

Ctrl+G

Go to line

Ctrl+O

Search by filename

Ctrl+P+number

Jump to line number

Ctrl+O+number +number

Jump to column

Ctrl+Shift+O

Go to member

Alt+W

Close active tab

Ctrl+Enter

Run snippet

Ctrl+M

Go to matching bracket

Ctrl+P+number

Jump to line number

Ctrl+O+number +number

Jump to column

Ctrl+/

Toggle comment

Ctrl+D

Select next occurrence

Ctrl+U

Undo last selection

Ctrl+E

Start / stop recording

Ctrl+S

Save timeline data

Ctrl+O

Open / Load timeline data

Ctrl+E

Start / stop recording

Arrow Right

Accept Suggestion

Arrow Up/Arrow Down

Previous / next command (line)

Ctrl+`

Focus the Console

Ctrl+L

Clear Console

Shift+Enter

Multi-line entry

Enter

Execute